The family was attended an elderly woman as a nurse, who in her infancy had been exposed the contagion the smallpox, but had resisted This woman was now infected, but had the disease in the slightest manner, a very few eruptions appearing, two or three which only maturated. From a solitary instance like that adduced Mary James, whose constitution appears have resisted the action the variolous virus, after the influence the cow-pox virus had been soon arrested in its progress, no positive conclusion can fairly drawn nor from the history the three other patients who were subsequently infected, but, nevertheless, the facts collectively may That one mild variety the smallpox has appeared I have already plainly shewn and the means now mentioned probably have in our power produce at will another. At the time when the pustule was destroyed in the arm Mary James I was informed she had been indisposed about twelve hours but I now assured those who were with her that the space time was much less. Be that as may, in cases cow-pox inoculation I would not recommend any application subdue the action the pustule until convincing proofs had appeared the patient's having felt its effects at least twelve hours. No harm, indeed, could ensue were a longer period elapse before the application was See Inquiry into the Causes and Effects the Variolæ good site to buy essays Vaccinæ, original made use In short, should suffered have as full an effect as could, consistently with the state the arm.

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As the cases inoculation multiply, I more and more convinced the extreme mildness the symptoms arising merely from the primary action the virus the constitution, and that those symptoms which, as in the accidental cow-pox, affect the patient with severity, are entirely secondary, excited the irritating processes inflammation and ulceration can you write my paper and appears that this singular virus possesses an irritating quality a peculiar kind, but as a single cow-pox pustule all that necessary render the variolous virus buy art research paper ineffectual, and as possess the means allaying the irritation, should any arise, becomes little or no conseq uence.

It appears then, as far as an inference can drawn from the present progress cow-pox inoculation, that an accidental circumstance only which can render this a violent disease, and a circumstance that nature which, fortunately, in the power almost everyone avoid. I allude the communication the disease from cows.

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In this case, should the hands the milker affected with cheap term paper writing service little accidental sores any extent, every sore would become the nidus infection and feel the influence the virus and the degree violence in the constitutional symptoms would in proportion the number and the state these local affections. Hence follows that a person, either accident or design, might filled with these wounds from contact with the virus that the constitution might sink under the pressure. Seeing that possess the means rendering the action the sores mild, which, when left chance, are capable producing violent effects and seeing, too, that these sores bear a resemblance the smallpox, especially the confluent, should not encourage the hope that some topical application might used with advantage counteract the fatal tendency that disease, when appears in this terrific form? At what stage or stages the disease this may done with the most promising expectation success I will not pretend now determine. I only throw out this idea as the basis further reasoning and experiment.

I have often been foiled in endeavours communicate the VACCINATION AGAINST SMALLPOX cow-pox inoculation. An inflammation will sometimes succeed the scratch or puncture, and in a few days disappear without producing any further effect. Sometimes will even produce an ichorous fluid, and yet the system will not aftected.

lO The same thing, know, happens with the smallpox virus. Four or five servants were inoculated at a farm contiguous this place, last summer, with matter just taken from an infected cow. A little inflammation appeared all their arms, but died away without producing a pustule yet all these servants caught the disease thin a write a good thesis month afterwards from milking the infected cows, and some them had severely. At present no other mode than that case study writers commonly practiced for inoculating the smallpox has been used for giving the cow-pox but probable this might varied with advantage.

We should imitate the casual communication more clearly were first, making the smallest superficial incision or puncture the skin, produce a little scab, and then, removing touch the abraded part with the virus. A small portion a thread imbrued in the virus as in the old method inoculating the smallpox and laid upon the slightly incised skin might probably prove a successful way giving the disease or the cutis might posed in a minute point an atom blistering plaster, and the virus brought in contact with In the cases just alluded where I did not succeed in giving the essay title help disease constitutionally, the experiment was made with matter taken in a purulent state from a Is pure pus, though contained in a smallpox pustule, ever capable producing the smallpox perfectly? I suspect not. Let consider that always preceded the limpid fluid, which, in constitutions susceptible variolous contagion, always infectious and though, opening a pustule, its contents may appear perfectly purulent, yet a given quantity the limpid fluid may, at the same time, blended with though would imperceptible the only test our senses, the someone help me write my thesis eye. The presence, then, this fluid, or its mechanical diffusion through pus, may at all times render active what apparently mere pus, while its total absence as in At this period the inquiry I had not discovered the importance inoculating with virus newly formed in the pustule. 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